Genetic Oestrogen


Genetic Estrogen-Being a Woman
Being a Woman


Oestrogen hormones affect the growth, differentiation
and function of a number of target tissues.

Improving oestrogen metabolism is of benefit to women who
suffer from oestrogen-dominant conditions such as
endometriosis, premenstrual syndrome and uterine
fibroid tumours, or where there is a family history of
breast, uterine or ovarian cancer, or prostate cancer
in men.
The importance of both oestrogen and progesterone
in breast cancer development is well established.
However, considerable inter-individual variability has
been observed in carcinogen metabolism, metabolism
of steroid hormones, and phase I and phase II
Variations in genes involved in these biological processes
help identify a sub-population of women and men
with higher lifetime exposure to oestrogens, oestrogen
metabolites and other carcinogens.

Understanding an individual’s genetic variability will allow for targeted diet, lifestyle and hormone intervention.
The DNAlysis Oestrogen Metabolism and Detoxification
test includes 10 genes involved in oestrogen
biosynthesis, oestrogen metabolism, and phase I and
phase II detoxification.

Genetic Oestrogen-Liver Detoxification
Liver Detoxification


  • The efficacy of oestrogen detoxification
  • The impact in risks of breast and prostate cancer
  • The impact of exposure to other pro-carcinogens such as smoking and nitrates
  • The ability to detoxify free radicals
  • The ability to detoxify xenobiotics and oxidative by-products
  • The ability to neutralise and eliminate the by-products of hormones as well as breakdown adrenaline and other catecholamines
  • Efficacy of Methylation which impacts on 1000’s of cellular activities, enzymes and hormones

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